An Improved Implementation of Codon Adaptation Index

نویسنده

  • Xuhua Xia
چکیده

Codon adaptation index is a widely used index for characterizing gene expression in general and translation efficiency in particular. Current computational implementations have a number of problems leading to various systematic biases. I illustrate these problems and provide a better computer implementation to solve these problems. The improved CAI can predict protein production better than CAI from other commonly used implementations.

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عنوان ژورنال:
  • Evolutionary Bioinformatics Online

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2007